Figure 3
Figure 3:  CXCR4 is a potential GPCR regulated by GNG4.
CXCR4 is a potential GPCR regulated by GNG4.
A) Volcano plot of correlation of RNA levels of GNG4 with that of all GPCRs in GBM samples of TCGA (n=572), CXCR4 is marked with black circle, B) Gene Ontology pathway enrichment analysis of GPCRs negatively correlating with GNG4. The number to the right side of each bar represents the number of genes enriched. Please note that, chemokine-chemokine receptor signaling got enriched multiple times (denoted by red box), C) Correlation of RNA level of GNG4 with that chemokine receptors CCR1, CCR2, CCR5, CCR7 and CXCR4 in all GBM samples in TCGA (n=572).

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