A) Role of CXCR4 downstream pathways, ERK and JNK pathways, in GBM cell migration. ERK and JNK pathways were inhibited by respective inhibitors and migration of U87MG cells were tested in Boyden chamber, B) Quantification for the same experiment, C) Levels of phospho-Mek1 in CXCR4 high-GNG4 high and CXCR4 high-GNG4 low conditions, D) Levels of phospho-Jnk in CXCR4 high-GNG4 high and CXCR4 high-GNG4 low conditions, E) Levels of phospho-Akt (Ser473 and Thr308) in CXCR4 high-GNG4 high and CXCR4 high-GNG4 low conditions. p-value was calculated by Student’s t test where *, ** and *** represents p-value of < 0.05, < 0.01 and < 0.001 respectively.