Genes & Cancer

Volume 5: Issue 9-10, September 2014

pp303-374

Issue 9-10, September 2014

About the Cover

The cover for Genes & Cancer features figure 9E ("TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer") from Singha et al.

Research Perspective

Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter

https://doi.org/10.18632/genesandcancer.34

Magdalena  A.  Cichon, Derek  C.  Radisky

p 303-305

Abstract |  PDF |  Full Text |  How to Cite

Research Papers

Telomere dysfunction suppresses multiple endocrine neoplasia in mice

https://doi.org/10.18632/genesandcancer.31

Ji-Hyeon   Lee, Miriam   Anver, Maria   Kost-Alimova, Alexei   Protopopov, Ronald  A. DePinho, Sushil  G. Rane

p 306-319

Abstract |  PDF |  Full Text |  How to Cite

TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer

https://doi.org/10.18632/genesandcancer.30

Prajjal  K. Singha, Srilakshmi   Pandeswara, Hui   Geng, Rongpei   Lan, Manjeri  A.  Venkatachalam , Pothana   Saikumar

p 320-336

Abstract |  PDF |  Full Text |  Supplementary Materials |  How to Cite

Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

https://doi.org/10.18632/genesandcancer.29

Xiaobing   Deng, Eileen   Friedman

p 337-347

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Generation of a mouse model of T-cell lymphoma based on chronic LPS challenge and TGF-β signaling disruption

https://doi.org/10.18632/genesandcancer.32

Nina M. Muñoz, Lior H. Katz, Ji-Hyun  Shin, Young Jin Gi, Vipin Kumar Menon, Mihai  Gagea, Asif  Rashid, Jian  Chen, Lopa  Mishra

p 348-352

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miR-155 induced transcriptome changes in the MCF-7 breast cancer cell line leads to enhanced mitogen activated protein kinase signaling

https://doi.org/10.18632/genesandcancer.33

Elizabeth C. Martin, Adrienne E. Krebs, Hope E. Burks, Steven  Elliott, Melody  Baddoo, Bridgette M. Collins-Burow, Erik K. Flemington, Matthew E. Burow

p 353-364

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The apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanisms

https://doi.org/10.18632/genesandcancer.28

Tanja   Haag, Christina  E. Herkt, Sara  K. Walesch, Antje  M. Richter, Reinhard  H. Dammann

p 365-374

Abstract |  PDF |  Full Text |  How to Cite