Genes & Cancer

Volume 6: Issue 3-4, March 2015

pp82-181

Issue 3-4, March 2015

About the Cover

The cover for Genes & Cancer features figure S6 (“EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma”) from Fadul et al.

Editorials

Biguanides and targeted anti-cancer treatments

https://doi.org/10.18632/genesandcancer.59

Elyse K. Hanly, Zbigniew  Darzynkiewicz, Raj K. Tiwari

p 82-83

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Reviews

Trop2 and its overexpression in cancers: regulation and clinical/ therapeutic implications

https://doi.org/10.18632/genesandcancer.40

Anna  Shvartsur, Benjamin  Bonavida

p 84-105

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Research Papers

Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma

https://doi.org/10.18632/genesandcancer.53

Honglin  Chen, James  Lee, Noelyn M. Kljavin, Benjamin  Haley, Anneleen  Daemen, Leisa  Johnson, Yuxin   Liang

p 106-118

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Drug sensitivity profiling and molecular characteristics of cells from pleural effusions of patients with lung adenocarcinoma

https://doi.org/10.18632/genesandcancer.56

Rita  Ötvös, Adam  Szulkin, Carl-Olof  Hiilerdal, Aytekin  Celep, Eviane  Yousef-Fadhel, Henriette  Skribek, Anders  Hjerpe, Laszlo  Szekely, Katalin  Dobra

p 119-128

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EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma

https://doi.org/10.18632/genesandcancer.57

John  Fadul, Russell  Bell, Laura M. Hoffman, Mary C. Beckerle, Michael E. Engel, Stephen L. Lessnick

p 129-143

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Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

https://doi.org/10.18632/genesandcancer.55

Blake  A. Jacobson, Esther  Z. Chen, Shaogeng   Tang, Holly  Sedgwick  Belgum, Joel  A. McCauley, Kristen  A. Evenson, Ryan  G. Etchison, Joe   Jay-Dixon, Manish  R. Patel, Ahmad   Raza, Ashok  K. Saluja, Jonathan   D’Cunha, Robert  A. Kratzke

p 144-152

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Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer

https://doi.org/10.18632/genesandcancer.58

Jennifer E. Yeh, Simion  Kreimer, Sarah R. Walker, Megan M. Emori, Hannah  Krystal, Andrea  Richardson, Alexander R. Ivanov, David A. Frank

p 153-168

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Suberoylanilide hydroxamic acid (SAHA) reverses chemoresistance in head and neck cancer cells by targeting cancer stem cells via the downregulation of nanog

https://doi.org/10.18632/genesandcancer.54

Bhavna  Kumar, Arti  Yadav, James C. Lang, Theodoros N. Teknos, Pawan  Kumar

p 169-181

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