Genes & Cancer

Press Release Archive

New High-Efficiency Gene Editing Method Enhances Speed and Reduces Costs in Biomedical Research

November 6, 2025
“Thus, this new site-specific and cassette mutagenesis method is highly efficient, fast and versatile, likely resulting in its wide use for typical biomedical research, as well as for engineering and refining synthetic or mutant proteins from AI-assisted design.” BUFFALO, NY — November 6, 2025 — A new research paper was published in Volume 16 of Genes & Cancer on October 31, 2025, titled “P3a site-specific and cassette mutagenesis for seamless protein, RNA... continue reading >>

Epstein-Barr Virus Protein EBNA1 Upregulates Oncogenes in Cervical Cancer Cells

August 22, 2025
“Our findings suggest that increase expression levels of Derlin1 and PSMD10 genes in HeLa cells by the EBV-EBNA1 might induce cancer cell survival and accelerates the development of cervical cancer (CC).” BUFFALO, NY — August 22, 2025 — A new research paper was published in Volume 16 of Genes & Cancer on August 6, 2025, titled "Epstein-Barr virus nuclear antigen 1 upregulates Derlin1 and PSMD10 expression in HeLa cells." In this study, led by first authors Amir... continue reading >>

Genes & Cancer Sponsors Open Access Team in 2025 Ride for Roswell

June 10, 2025
“Impact Journals, publisher of Genes & Cancer, is once again proudly sponsoring the Open Access Team in the annual Ride for Roswell.” BUFFALO, NY — June 10, 2025 — The Ride for Roswell, one of the USA’s largest cycling events supporting cancer research, returns to Buffalo on Saturday, June 28, 2025. Hosted annually by Roswell Park Comprehensive Cancer Center, this community-wide event brings together riders, volunteers, and supporters to raise... continue reading >>

New Study Identifies lncRNAs CBR3-AS1 and PCA3 as Potential Biomarkers for Early Detection of Gastric Cancer

June 5, 2025
"In GC, CBR3-AS1 and PCA3 may be utilized as therapeutic targets and prognostic biomarkers, respectively." BUFFALO, NY- June 5, 2025 – A new research paper was published in Volume 16 of Genes & Cancer on May 9, 2025, titled "Evaluation of LncRNAs CBR3-AS1 and PCA3 expression in Gastric cancer and their correlation to clinicopathological variables." Researchers, led by first author Parisa Najari and corresponding author Reza Safaralizadeh from the University of Tabriz,... continue reading >>

Genes & Cancer Participation at SSP 47th Annual Meeting in Baltimore

May 5, 2025
Impact Journals is pleased to participate as an exhibitor at the Society for Scholarly Publishing (SSP) 47th Annual Meeting from May 28–30, 2025, in Baltimore, Maryland. BUFFALO, NY – May 5, 2025 – Impact Journals (Genes & Cancer’s publisher) is pleased to announce its participation as an exhibitor at the upcoming Society for Scholarly Publishing (SSP) 47th Annual Meeting. The event will take place from May 28-30, 2025, in Baltimore, Maryland. Attendees are invited... continue reading >>

Genes & Cancer to Participate at the AACR Annual Meeting 2025

March 17, 2025
Impact Journals is proud to participate in the American Association for Cancer Research (AACR) Annual Meeting 2025, taking place April 25-30 in Chicago, Illinois. BUFFALO, NY – March 17, 2025 – Impact Journals (Genes & Cancer’s publisher) is pleased to announce its participation as an exhibitor at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2025. The meeting is scheduled for April 25-30, 2025, at the McCormick Place Convention... continue reading >>

Pathogenic Variants in Retinoblastoma Suggest a Potential Gain-of-Function Mutation

January 29, 2025
“In other words, the pR552* mutant behaves more like a gain-of-function or oncogenic mutant. Indeed, a family carrying this mutation showed complete penetrance and high expressivity.” BUFFALO, NY- January 29, 2025 – A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, “Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation.” Researchers from Instituto de Física... continue reading >>

Dialyl-Sulfide and Trans-Chalcone Prevent Breast Cancer by Targeting SULT1E1 and HIF1a-MMPs

August 23, 2024
“For the first time, we are revealing that advanced cancer tissue with elevated SULT1E1-protein may reactivate in a reducing-state initiated by chalcone, but remain dormant in an oxidative environment.” BUFFALO, NY- August 23, 2024 – A new research paper was published in Genes & Cancer on August 9, 2024, entitled, “Dialyl-sulfide with trans-chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs... continue reading >>

Genes & Cancer Sponsors 2024 Ride for Roswell

June 11, 2024
“Impact Journals (Genes & Cancer's publisher) is sponsoring Team Open Access in the annual cycling event to end cancer: The Ride for Roswell. This fundraiser is hosted by Roswell Park Comprehensive Cancer Center in Buffalo, New York.” BUFFALO, NY- June 11, 2024 – The Ride for Roswell is one of the nation’s largest cycling events—hosted by Roswell Park Comprehensive Cancer Center—to raise awareness and funds for cancer research and patient care. This... continue reading >>

Inhibitory Effect of miR-377 on Prostate Cancer Cells

May 21, 2024
“Our research findings suggest that miR-377 could potentially serve as a valuable therapeutic strategy for the treatment of prostate cancer (PCa).” BUFFALO, NY- May 21, 2024 – A new research paper was published in Genes & Cancer on May 16, 2024, entitled, “Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4.” The MYC... continue reading >>

Genes & Cancer at SSP 46th Annual Meeting

May 13, 2024
BUFFALO, NY- May 13, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Genes & Cancer is one of the most prominent journals published by Impact Journals. Impact Journals is proud to participate as an exhibitor at the Society for Scholarly Publishing (SSP) 46th Annual Meeting, which convenes in Boston, Massachusetts, at the Westin Boston Seaport District from May 29–31, 2024. This... continue reading >>

Genes & Cancer at AACR Annual Meeting 2024

March 11, 2024
BUFFALO, NY- March 11, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Genes & Cancer is one of the most prominent journals published by Impact Journals. Impact Journals will be participating as an exhibitor at the American Association for Cancer Research (AACR) Annual Meeting 2024 from April 5-10 at the San Diego Convention Center in San Diego, California. This year, the AACR meeting theme is... continue reading >>

The Roles of USP1 in Ewing Sarcoma

February 14, 2024
“This study uncovered important roles for USP1 in Ewing sarcoma.” BUFFALO, NY- February 14, 2024 – A new research paper was published in Genes & Cancer on February 5, 2024, entitled, “Roles of USP1 in Ewing sarcoma.” Ewing sarcoma is a cancer of bone and soft tissue in children and young adults that is driven by the EWS-ETS fusion transcription factor, most commonly EWS-FLI1. Researchers Panneerselvam Jayabal, Xiuye Ma and Yuzuru Shiio from The... continue reading >>

Mechanistically Based Blood Proteomic Markers in the TGF-β Pathway Stratify Risk of HCC in Patients With Cirrhosis

February 9, 2024
“A fundamental hypothesis we sought to test was whether biomarkers from the TGF-β signaling pathway might be of novel value in risk stratification of HCC in the clinical cirrhotic setting.” BUFFALO, NY- February 9, 2024 – A new research paper was published in Genes & Cancer on February 5, 2024, entitled, “Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with... continue reading >>

Increased BRD4-L and BRD4-S Promotes Chemotherapy Resistance in Ovarian Carcinoma

September 13, 2023
“Overall, our work revealed a strong positive correlation between BRD4 overexpression status and chemoresistance in ovarian cancer […]” BUFFALO, NY- September 13, 2023 – A new research paper was published in Genes & Cancer on September 12, 2023, entitled, “Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma.” Chemoresistance in ovarian carcinoma is a... continue reading >>

A Novel Chromosomal Abnormality in AML Patient: Case Report and Literature Review

July 7, 2023
“Here we report an unusual association of t (5; 17) with t (8; 21) in AML and we try to discuss the prognosis of this association and then the treatment.” BUFFALO, NY- July 7, 2023 – A new research paper was published in Genes & Cancer on June 28, 2023, entitled, “A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature.” The t (8; 21) (q22; q22) with the... continue reading >>

Impact Journals Sponsors 2023 Ride for Roswell

June 23, 2023
Genes & Cancer's publisher, Impact Journals, is sponsoring Team Open Access in the annual cycling event to end cancer: The Ride for Roswell. BUFFALO, NY- June 19, 2023 – The Ride for Roswell is one of the nation’s largest cycling events—hosted by Roswell Park Comprehensive Cancer Center—to raise awareness and funds for cancer research and patient care. This charity bike ride, based out of Buffalo, New York, has brought people together for 27 years to... continue reading >>

Genes & Cancer at AACR Annual Meeting 2023

April 4, 2023
Impact Journals (Genes & Cancer's publisher) is proud to participate at the American Association for Cancer Research (AACR) Annual Meeting 2023, which convenes April 14-19 in Orlando, Florida. BUFFALO, NY- April 4, 2023 – Impact Journals will be participating as an exhibitor at the American Association for Cancer Research (AACR) Annual Meeting 2023 from April 14-19 at the Orange County Convention Center in Orlando, Florida. This year, the AACR meeting theme is: “Advancing... continue reading >>

Genes & Cancer | VCP/p97 as a Therapeutic Target in KRAS-Mutant Pancreatic Cancer

March 24, 2023
“In summary, our goal was to identify additional therapeutic targets for KRAS-driven PDAC.” Your browser does not support the audio element. BUFFALO, NY- March 24, 2023 – A new research paper was published in Genes & Cancer on March 10, 2023, entitled, “VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer.” Researchers have recently shown that... continue reading >>

Genes & Cancer | Severe Herpesvirus Infection Beats Adult T-cell Leukemia/Lymphoma

February 24, 2023
“Although contracting herpes simplex or herpes zoster is unpleasant, the mechanism by which these herpesvirus infections can produce a therapeutic effect […]” Listen to an audio version of this press release BUFFALO, NY- February 24, 2023 – A new editorial was published in Genes & Cancer on January 19, 2023, entitled, “Severe herpesvirus infection beats adult T-cell leukemia/lymphoma.” In this recently published editorial, researcher... continue reading >>

Genes & Cancer | CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens

February 10, 2023
PRESS RELEASE: A new review was published in Genes & Cancer on February 1, 2023, entitled, “CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens.” Listen to an audio version of this press release BUFFALO, NY- February 10, 2023 – A new review was published in Genes & Cancer on February 1, 2023, entitled, “CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens.” “Carcinoembryonic antigen (CEA), one of few... continue reading >>

Genes & Cancer | Leveraging Allogeneic Dendritic Cells for Neoantigen Cancer Vaccines

February 3, 2023
PRESS RELEASE: On January 30, 2023, a new research perspective was published in Genes & Cancer, entitled, “Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines.” Listen to an audio version of this press release BUFFALO, NY- February 3, 2023 – A new research perspective was published in Genes & Cancer on January 30, 2023, entitled, “Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based... continue reading >>

Genes & Cancer | Slit2 signaling stimulates Ewing sarcoma growth

January 13, 2023
“Using secretome proteomics, we found that EWS::FLI1 induces the expression of Slit2. We demonstrate that EWS::FLI1 binds to the gene promoter of Slit2 and activates its expression.” Listen to an audio version of this press release BUFFALO, NY- January 13, 2023 – A new research paper was published in Genes & Cancer on December 14, 2022, entitled, “Slit2 signaling stimulates Ewing sarcoma growth.” Ewing sarcoma is a cancer of bone and soft tissue in... continue reading >>

Genes & Cancer | Pathogenesis to management of hepatocellular carcinoma

January 6, 2023
On December 13, 2022, Genes & Cancer published a new review, entitled, “Pathogenesis to management of hepatocellular carcinoma.” — Listen to an audio version of this press release BUFFALO, NY- January 6, 2023 – A new review was published in Genes & Cancer on December 13, 2022, entitled, “Pathogenesis to management of hepatocellular carcinoma.” In this review, researchers Ben L. Da, Kelly I. Suchman, Lawrence Lau, Atoosa Rabiee, Aiwu... continue reading >>